{"product_id":"hpe-proliant-dl380-gen10-plus-16-bay-build-your-own","title":"HPE ProLiant DL380 Gen10+ 16-Bay 2.5\" Drives","description":"\u003cp\u003eThe DL380 Gen10+ 16-Bay 2.5\" brings the Gen10+ platform advantages — Ice Lake Xeon, PCIe Gen4, 32 DIMM slots, vSAN ESA support — to a 16-bay SFF density configuration. This is the Gen10+ platform for vSAN all-flash ESA clusters, high-density NVMe storage tiers, and converged workloads requiring more than 8 SFF bays with the full Gen10+ feature set.\u003c\/p\u003e\u003cp\u003eFor full Gen10+ platform details (Ice Lake processors, memory architecture, PCIe Gen4 advantages, vSAN ESA requirements, Smart Array controllers, iLO 5) see the \u003ca href=\"\/products\/hpe-proliant-dl380-gen10-plus-8-bay-build-your-own\"\u003eDL380 Gen10+ 8-Bay page\u003c\/a\u003e. This page covers the 16-bay storage story and when it makes sense over the 8-bay or 24-bay Gen10+ configurations.\u003c\/p\u003e\u003chr\u003e\u003ch2\u003eStorage — 16 SFF Bays with Gen4 NVMe\u003c\/h2\u003e\u003cp\u003eSixteen 2.5\" hot-swap bays. PCIe Gen4 NVMe backplane available on Gen10+ — NVMe drives connect at full Gen4 bandwidth. For vSAN ESA all-flash clusters, 16 NVMe drives per node enables multiple ESA storage pools per node with meaningful capacity and IOPS per chassis.\u003c\/p\u003e\u003cul\u003e  \u003cli\u003e\n\u003cstrong\u003evSAN ESA all-flash:\u003c\/strong\u003e 16 NVMe drives across 16 bays — all drives participate in the unified ESA storage pool. No cache\/capacity split — ESA manages its own tiering internally. 25 GbE minimum for ESA; 100 GbE recommended for high-density nodes.\u003c\/li\u003e  \u003cli\u003e\n\u003cstrong\u003evSAN OSA hybrid or all-flash:\u003c\/strong\u003e SSD cache tier + SAS\/SATA HDD capacity tier. 16 bays supports larger disk groups with better cache\/capacity ratios than 8-bay configurations.\u003c\/li\u003e  \u003cli\u003e\n\u003cstrong\u003eHigh-density SAS SSD storage:\u003c\/strong\u003e 16x SAS SSDs at RAID 10 for database and analytics tiers requiring high-endurance SSD performance without NVMe latency requirements.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eGen10+ vs. Gen10 16-Bay for vSAN:\u003c\/strong\u003e The Gen10+ 16-Bay supports vSAN ESA (ESA requires NVMe + Gen10+ minimum). Gen10 16-Bay is OSA-only. If your vSAN target is ESA, Gen10+ is required. If OSA on vSphere 7.x is your target, Gen10 delivers comparable performance at lower cost.\u003c\/p\u003e\u003chr\u003e\u003ch2\u003eOur Assessment\u003c\/h2\u003e\u003cp\u003eThe DL380 Gen10+ 16-Bay is the premium vSAN ESA and high-density NVMe storage configuration — justified when vSAN ESA is the target, PCIe Gen4 NVMe performance is required, or the deployment lifecycle extends to 2030+. For OSA deployments or shorter lifecycle projects, the Gen10 16-Bay provides comparable storage density at meaningfully lower acquisition cost.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eUpgrade context:\u003c\/strong\u003e Replaces → \u003ca href=\"\/products\/dl380-g10-2-5-16-bay-server\"\u003eDL380 Gen10 16-Bay\u003c\/a\u003e when ESA\/Gen4 justified. Step up from → \u003ca href=\"\/products\/hpe-proliant-dl380-gen10-plus-8-bay-build-your-own\"\u003eDL380 Gen10+ 8-Bay\u003c\/a\u003e when drive count needs to double. Step down from → \u003ca href=\"\/products\/hpe-proliant-dl380-gen10-plus-24-bay-build-your-own\"\u003eDL380 Gen10+ 24-Bay\u003c\/a\u003e when 16 bays covers the storage design.\u003c\/p\u003e\u003chr\u003e\u003ch2\u003eWorkload Fit\u003c\/h2\u003e\u003ctable\u003e  \u003ctr\u003e\n\u003cth\u003eThis server excels at\u003c\/th\u003e\n\u003cth\u003eConsider alternatives for\u003c\/th\u003e\n\u003c\/tr\u003e  \u003ctr\u003e\n\u003ctd\u003e✅ vSAN ESA all-flash (16 NVMe per node)\u003c\/td\u003e\n\u003ctd\u003e❌ vSAN OSA on vSphere 7.x (Gen10 sufficient)\u003c\/td\u003e\n\u003c\/tr\u003e  \u003ctr\u003e\n\u003ctd\u003e✅ High-density Gen4 NVMe storage tiers\u003c\/td\u003e\n\u003ctd\u003e❌ 8 bays sufficient (Gen10+ 8-Bay lower cost)\u003c\/td\u003e\n\u003c\/tr\u003e  \u003ctr\u003e\n\u003ctd\u003e✅ Converged workloads requiring 16 SFF bays + Ice Lake\u003c\/td\u003e\n\u003ctd\u003e❌ LFF drives needed\u003c\/td\u003e\n\u003c\/tr\u003e  \u003ctr\u003e\n\u003ctd\u003e✅ Infrastructure lifecycle 5+ years + vSAN ESA\u003c\/td\u003e\n\u003ctd\u003e❌ Budget-primary shorter lifecycle\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003chr\u003e\u003ch2\u003eReady to Configure?\u003c\/h2\u003e\u003cp\u003eTell us your vSAN architecture (ESA or OSA), NVMe vs. SAS\/SATA preference, Ice Lake CPU target, memory requirement, and quantity. We'll return formal pricing alongside Gen10 and Gen10+ 8-Bay comparisons. Volume pricing at 5 units and above.\u003c\/p\u003e","brand":"HPE","offers":[{"title":"Default Title","offer_id":45951283134663,"sku":"BP-012711","price":6462.65,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/4493\/0247\/files\/server-design-lab-hpe-proliant-dl380-gen10-16-bay-25-drives-874519.png?v=1765539623","url":"https:\/\/wholesaleservers.com\/products\/hpe-proliant-dl380-gen10-plus-16-bay-build-your-own","provider":"Wholesale Servers","version":"1.0","type":"link"}