HPE ProLiant DL380 Gen10+ 24-Bay 2.5" Drives
The DL380 Gen10+ 24-Bay 2.5" is the maximum SFF density configuration on the Gen10+ platform — twenty-four hot-swap bays with PCIe Gen4 NVMe backplane support, Ice Lake Xeon, 32 DIMM slots, and vSAN ESA compatibility. For HPE shops building the largest vSAN ESA clusters, high-density NVMe-oF storage targets, or Ceph deployments at maximum per-node drive count with the newest platform generation, this is the configuration.
For full Gen10+ platform details see the DL380 Gen10+ 8-Bay page.
Storage — 24 SFF Bays + Gen4 NVMe
Twenty-four 2.5" hot-swap bays with PCIe Gen4 NVMe backplane. At full NVMe population, Gen4 NVMe SSDs at 24 bays deliver aggregate sequential read throughput exceeding 100 GB/s — a scale of storage performance not achievable on Gen10 platforms. Common configurations:
- vSAN ESA all-flash: 24 Gen4 NVMe drives in unified ESA storage pool. Maximum vSAN ESA capacity and IOPS per node in the DL380 Gen10+ family. ESA requires Smart Array E208i-a HBA mode for direct drive pass-through.
- NVMe-oF storage targets: 24 Gen4 NVMe drives as a disaggregated storage target serving multiple compute hosts via NVMe over Fabrics. 100 GbE required to avoid network becoming the throughput ceiling.
- Ceph NVMe OSD nodes: 24 Gen4 NVMe OSDs per node at maximum per-node drive density. HBA mode for direct drive access by Ceph processes.
- All-SAS SSD or hybrid: SAS/SATA drives continue to work on Gen10+ backplanes for shops not requiring NVMe — same 24-bay flexibility as Gen10 but with Gen10+ compute advantages.
24-Bay vs. 16-Bay Gen10+: If 16 NVMe drives per node covers your vSAN ESA or storage design, the 16-Bay is the lower-cost choice. The 24-Bay earns its premium when maximum per-node drive count is a specific design requirement — typically for large vSAN clusters optimizing per-node storage cost/TB or NVMe-oF targets where aggregate per-node throughput is the design variable.
Our Assessment
The most capable SFF storage configuration in the HPE DL380 Gen10+ family. Justified when maximum Gen4 NVMe drive density per 2U node is the design target. For most Gen10+ deployments, the 8-Bay or 16-Bay covers the storage requirement at lower cost — the 24-Bay is for large-scale storage-primary deployments where every additional NVMe drive per node improves cluster economics.
Navigation: Step down → DL380 Gen10+ 16-Bay. Gen10 equivalent → DL380 Gen10 24-Bay.
Workload Fit
| This server excels at | Consider alternatives for |
|---|---|
| ✅ vSAN ESA maximum per-node NVMe density | ❌ 16 bays sufficient (Gen10+ 16-Bay lower cost) |
| ✅ NVMe-oF storage targets at Gen4 bandwidth | ❌ vSAN OSA (Gen10 24-Bay sufficient) |
| ✅ Ceph Gen4 NVMe OSD nodes (24 OSDs/node) | ❌ LFF drives preferred |
| ✅ Maximum per-node Gen4 NVMe capacity | ❌ Budget-primary deployments |
Ready to Configure?
Tell us your storage architecture (vSAN ESA, NVMe-oF, Ceph), drive type, Ice Lake CPU preference, memory target, and quantity. Volume pricing at 5 units and above.
HPE Proliant DL380 Gen10+ 24-Bay 2.5"
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Storage Drives Select up to 24 drives (0/24 Slots Used)
Selecting SATA HDD will disable NVMe selections
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