HPE ProLiant DL380 Gen10+ 16-Bay 2.5" Drives
HPE Proliant DL380 Gen10+ 16-Bay 2.5"
Configure Your System:
Processor
Memory (RAM)
RAID Controllers
Storage Drives
Select up to 16 drives
(0/16 Slots Used)
Selecting SATA HDD will disable NVMe selections
Remote Access
Power Supply
If you are planning to add-on a GPU, we recommend selecting the highest TDP power supply to ensure optimization
Network Cards
Selecting a high-speed Ethernet card does not guarantee network speed if the rest of the network is slower
Operating System
Choose The Right System For You
HPE DL380 Gen10+ Enterprise-Grade Server
What's Included
Server Warranty
Add Ons
The DL380 Gen10+ 16-Bay 2.5" brings the Gen10+ platform advantages — Ice Lake Xeon, PCIe Gen4, 32 DIMM slots, vSAN ESA support — to a 16-bay SFF density configuration. This is the Gen10+ platform for vSAN all-flash ESA clusters, high-density NVMe storage tiers, and converged workloads requiring more than 8 SFF bays with the full Gen10+ feature set.
For full Gen10+ platform details (Ice Lake processors, memory architecture, PCIe Gen4 advantages, vSAN ESA requirements, Smart Array controllers, iLO 5) see the DL380 Gen10+ 8-Bay page. This page covers the 16-bay storage story and when it makes sense over the 8-bay or 24-bay Gen10+ configurations.
Storage — 16 SFF Bays with Gen4 NVMe
Sixteen 2.5" hot-swap bays. PCIe Gen4 NVMe backplane available on Gen10+ — NVMe drives connect at full Gen4 bandwidth. For vSAN ESA all-flash clusters, 16 NVMe drives per node enables multiple ESA storage pools per node with meaningful capacity and IOPS per chassis.
- vSAN ESA all-flash: 16 NVMe drives across 16 bays — all drives participate in the unified ESA storage pool. No cache/capacity split — ESA manages its own tiering internally. 25 GbE minimum for ESA; 100 GbE recommended for high-density nodes.
- vSAN OSA hybrid or all-flash: SSD cache tier + SAS/SATA HDD capacity tier. 16 bays supports larger disk groups with better cache/capacity ratios than 8-bay configurations.
- High-density SAS SSD storage: 16x SAS SSDs at RAID 10 for database and analytics tiers requiring high-endurance SSD performance without NVMe latency requirements.
Gen10+ vs. Gen10 16-Bay for vSAN: The Gen10+ 16-Bay supports vSAN ESA (ESA requires NVMe + Gen10+ minimum). Gen10 16-Bay is OSA-only. If your vSAN target is ESA, Gen10+ is required. If OSA on vSphere 7.x is your target, Gen10 delivers comparable performance at lower cost.
Our Assessment
The DL380 Gen10+ 16-Bay is the premium vSAN ESA and high-density NVMe storage configuration — justified when vSAN ESA is the target, PCIe Gen4 NVMe performance is required, or the deployment lifecycle extends to 2030+. For OSA deployments or shorter lifecycle projects, the Gen10 16-Bay provides comparable storage density at meaningfully lower acquisition cost.
Upgrade context: Replaces → DL380 Gen10 16-Bay when ESA/Gen4 justified. Step up from → DL380 Gen10+ 8-Bay when drive count needs to double. Step down from → DL380 Gen10+ 24-Bay when 16 bays covers the storage design.
Workload Fit
| This server excels at | Consider alternatives for |
|---|---|
| ✅ vSAN ESA all-flash (16 NVMe per node) | ❌ vSAN OSA on vSphere 7.x (Gen10 sufficient) |
| ✅ High-density Gen4 NVMe storage tiers | ❌ 8 bays sufficient (Gen10+ 8-Bay lower cost) |
| ✅ Converged workloads requiring 16 SFF bays + Ice Lake | ❌ LFF drives needed |
| ✅ Infrastructure lifecycle 5+ years + vSAN ESA | ❌ Budget-primary shorter lifecycle |
Ready to Configure?
Tell us your vSAN architecture (ESA or OSA), NVMe vs. SAS/SATA preference, Ice Lake CPU target, memory requirement, and quantity. We'll return formal pricing alongside Gen10 and Gen10+ 8-Bay comparisons. Volume pricing at 5 units and above.
HPE Proliant DL380 Gen10+ 16-Bay 2.5"
16-Bay 2.5"
Choose Processor
Clock Speed
2.80 GHz Up To 3.60 GHz
Core Count
8
Thread Count
16
Cache
12 MB
Clock Speed
2.10 GHz Up To 3.30 GHz
Core Count
12
Thread Count
24
Cache
18 MB
Clock Speed
2.40 GHz Up To 3.40 GHz
Core Count
16
Thread Count
32
Cache
24 MB
Clock Speed
2.30 GHz Up To 3.40 GHz
Core Count
20
Thread Count
40
Cache
30 MB
Clock Speed
2.30 GHz Up To 3.40 GHz
Core Count
10
Thread Count
20
Cache
15 MB
Clock Speed
3.20 GHz Up To 3.60 GHz
Core Count
8
Thread Count
16
Cache
12 MB
Clock Speed
3.00 GHz Up To 3.60 GHz
Core Count
12
Thread Count
24
Cache
18 MB
Clock Speed
2.10 GHz Up To 3.40 GHz
Core Count
24
Thread Count
48
Cache
36 MB
Clock Speed
2.80 GHz Up To 4.30 GHz
Core Count
16
Thread Count
32
Cache
22 MB
Clock Speed
2.00 GHz Up To 3.10 GHz
Core Count
28
Thread Count
56
Cache
42 MB
Clock Speed
2.00 GHz Up To 3.70 GHz
Core Count
24
Thread Count
48
Cache
33 MB
Clock Speed
2.20 GHz Up To 3.40 GHz
Core Count
28
Thread Count
56
Cache
42 MB
Clock Speed
2.40 GHz Up To 3.60 GHz
Core Count
24
Thread Count
48
Cache
36 MB
Clock Speed
2.20 GHz Up To 3.50 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
2.10 GHz Up To 3.40 GHz
Core Count
24
Thread Count
48
Cache
36 MB
Clock Speed
2.30 GHz Up To 4.20 GHz
Core Count
24
Thread Count
48
Cache
33 MB
Clock Speed
2.30 GHz Up To 3.50 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
2.20 GHz Up To 3.40 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
2.10 GHz Up To 3.50 GHz
Core Count
36
Thread Count
72
Cache
54 MB
Clock Speed
2.20 GHz Up To 3.40 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
3.10 GHz Up To 4.30 GHz
Core Count
18
Thread Count
36
Cache
24.75 MB
Clock Speed
2.60 GHz Up To 3.40 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
2.60 GHz Up To 3.40 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
3.00 GHz Up To 4.20 GHz
Core Count
24
Thread Count
48
Cache
33 MB
Clock Speed
2.40 GHz Up To 3.50 GHz
Core Count
36
Thread Count
72
Cache
54 MB
Clock Speed
2.80 GHz Up To 3.60 GHz
Core Count
32
Thread Count
64
Cache
48 MB
Clock Speed
2.40 GHz Up To 3.40 GHz
Core Count
38
Thread Count
76
Cache
57 MB
Clock Speed
2.60 GHz Up To 4.30 GHz
Core Count
28
Thread Count
56
Cache
38.50 MB
Clock Speed
2.30 GHz Up To 3.40 GHz
Core Count
40
Thread Count
80
Cache
60 MB
Clock Speed
2.90 GHz Up To 4.30 GHz
Core Count
28
Thread Count
56
Cache
38.50 MHz
Choose Storage
Condition
New
Capacity
240GB
Drive Type
SATA SSD
Condition
New
Capacity
480GB
Drive Type
SATA SSD
Condition
New
Capacity
1TB
Drive Type
SATA SSD
Condition
New
Capacity
2TB
Drive Type
SATA SSD
Condition
New
Capacity
480GB
Drive Type
SATA SSD
Condition
New
Capacity
960GB
Drive Type
SATA SSD
Condition
New
Capacity
1.92TB
Drive Type
SATA SSD
Condition
New
Capacity
3.84TB
Drive Type
SATA SSD
Condition
New
Capacity
250GB
Drive Type
SATA SSD
Condition
New
Capacity
500GB
Drive Type
SATA SSD
Condition
New
Capacity
1TB
Drive Type
SATA SSD
Condition
New
Capacity
2TB
Drive Type
SATA SSD
Condition
New
Capacity
1.92TB
Drive Type
SAS SSD
Condition
New
Capacity
3.84TB
Drive Type
SAS SSD
Condition
New
Capacity
480GB
Drive Type
SAS SSD
Condition
New
Capacity
960GB
Drive Type
SAS SSD
Condition
New
Capacity
960GB
Drive Type
SAS SSD
Condition
New
Capacity
1.2TB
Drive Type
SAS HDD
Condition
New
Capacity
1.92TB
Drive Type
SAS HDD
Condition
New
Capacity
1.8TB
Drive Type
SAS HDD
Condition
New
Capacity
2.4TB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
480GB
Drive Type
SAS SSD
Condition
Refurbished
Capacity
800GB
Drive Type
SAS SSD
Condition
Refurbished
Capacity
960GB
Drive Type
SAS SSD
Condition
Refurbished
Capacity
Drive Type
SAS SSD
Condition
Refurbished
Capacity
3.84TB
Drive Type
SAS SSD
Condition
Refurbished
Capacity
600GB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
600GB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
900GB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
1.2TB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
2.4TB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
1.8TB
Drive Type
SAS HDD
Condition
Refurbished
Capacity
2TB
Drive Type
SAS HDD
Condition
Capacity
Drive Type
Blanks and Trays
Condition
Capacity
Drive Type
Blanks and Trays
RAM FAQ
What Memory Types and Speeds Are Supported
This server supports both ECC Registered RDIMM and LRDIMM [DDR4 OR DDR5] memory. ECC registered memory includes a purpose-built chip that ensures parity between the memory modules and the memory controller within the processor(s). ECC functionality is built into most server memory, and helps in notifying the system if there is an error within the memory regarding data corruption on the module.
The maximum supported memory speed in any given server is dictated by the system's Processor(s). This [Server Model] can read memory at the following speeds:
( SELECT from: 2133MHz, 2400MHz, 2666MHz, 2933MHz, 3200MHz )
**See Memory Speed Reference Below
What Memory Types and Speeds Are Supported (TEST)
This server supports both ECC Registered RDIMM and LRDIMM [DDR4 OR DDR5] memory. ECC registered memory includes a purpose-built chip that ensures parity between the memory modules and the memory controller within the processor(s). ECC functionality is built into most server memory, and helps in notifying the system if there is an error within the memory regarding data corruption on the module.
The maximum supported memory speed in any given server is dictated by the system's Processor(s). This [Server Model] can read memory at the following speeds:
( SELECT from: 2133MHz, 2400MHz, 2666MHz, 2933MHz, 3200MHz )
**See Memory Speed Reference Below
Is An Enterprise License Right For Me?
Determining if an iDRAC Enterprise License is right for you depends on your IT management needs and infrastructure complexity. Here are key considerations: When an iDRAC Enterprise License is a Good Fit: - Advanced Remote Management: You need features like virtual media, automated firmware updates, or remote console access for managing servers efficiently. - 24/7 Monitoring: You require constant, secure access to monitor and control servers, even when the operating system is down. -Large or Distributed Infrastructure: You manage multiple servers across locations and need centralized, reliable remote access to reduce downtime. - Time-Saving Operations: You value tools that simplify and automate maintenance tasks, minimizing the need for physical server visits. - Enhanced Security: You need advanced features like two-factor authentication or secure erase capabilities for compliance. - Cost of Downtime: The cost of server downtime outweighs the investment in advanced management tools. When You May Not Need It: - Small Scale Operations: If you manage only a few servers and can easily access them physically when needed. - Basic Needs: If you only require essential monitoring and management features available in the iDRAC Express license. Recommendation: If uptime, remote management, and advanced capabilities are critical to your operations, the iDRAC Enterprise License is a worthwhile investment. For smaller environments with fewer demands, a standard iDRAC license may suffice.
Choosing The Right Power Supply
Choosing the right server power supply is crucial for optimizing performance, efficiency, and reliability. Here’s a guide to help you make the right decision: 1. Understand Your Power Requirements: Server Configuration: Calculate the total power needs of all components, including CPUs, GPUs, RAM, storage, and networking cards. Future Scalability: Account for potential upgrades to ensure the power supply can handle increased loads. 2. Efficiency Rating Look for 80 PLUS Certification (Bronze, Silver, Gold, Platinum, or Titanium). Higher efficiency reduces energy costs and heat output. 3. Redundancy Options Consider redundant power supplies for critical systems to ensure uninterrupted operation during a failure. 4. Form Factor Compatibility Ensure the power supply fits the physical dimensions and connections required by your server chassis. 5. Power Capacity Choose a power supply that provides 20-30% headroom above your calculated requirements for optimal efficiency and reliability. 6. Hot-Swap Capability For enterprise environments, select hot-swappable units to minimize downtime during maintenance or replacements. Key Tip: Always consult the server’s technical documentation for recommended power supply specifications, and choose models certified for your hardware. Properly matching your power supply ensures stable operation and reduces long-term operational costs.
Save Your Design
Click the Add to Quote button at the bottom of your screen to save your design as a draft order for future reference and to check for discounts, lead time, and availability. Most servers ship within 1-3 days.
