HPE Proliant DL380 G10 Servers

The HPE ProLiant DL380 Gen10 is a highly versatile, enterprise-class 2U rackmount server built for performance, scalability, and security across a wide range of workloads. Designed to adapt to changing business needs, it delivers outstanding compute density, flexible storage configurations, and advanced management capabilities. Powered by dual Intel Xeon Scalable processors and engineered for high availability, the DL380 Gen10 is ideal for virtualization, cloud services, big data analytics, and mission-critical applications.

Performance

The DL380 Gen10 supports dual Intel Xeon Scalable processors (1st or 2nd Gen) from the Silver, Gold, and Platinum families, offering up to 28 cores per CPU and 56 cores total in a dual-socket setup. It leverages features such as Intel AVX-512, Hyper-Threading, and Turbo Boost Technology to deliver high compute performance for both general-purpose and compute-intensive workloads. With a maximum processor TDP of up to 205W per socket, the DL380 Gen10 can handle demanding tasks such as large-scale virtualization, in-memory databases, and high-performance analytics.

Memory and Scalability

The DL380 Gen10 supports up to 3.0TB of HPE DDR4 SmartMemory or Intel Optane Persistent Memory in 24 DIMM slots. It accommodates RDIMM or LRDIMM modules with speeds up to 2933 MT/s or 3200 MT/s, depending on the processor generation. Advanced memory features such as ECC, online spare, memory mirroring, and fast fault tolerance ensure optimal performance and system uptime, making it suitable for memory-intensive workloads and virtualized environments.

Storage Flexibility

One of the DL380 Gen10’s biggest strengths is its highly adaptable storage configuration:

• Support for 8 to 30 SFF (2.5”) SAS/SATA/NVMe drives or 4 to 20 LFF (3.5”) SAS/SATA drives
• Option for mixed drive types within the same chassis
• Support for NVMe drives for ultra-fast data access
• M.2 boot options for OS deployment
• Compatible with HPE Smart Array controllers such as the P408i-a, P816i-a, and P408e-p, offering RAID levels 0, 1, 5, 6, 10, 50, and 60
  

This flexibility allows organizations to configure the DL380 Gen10 for high-performance transactional workloads, balanced hybrid setups, or high-capacity storage solutions.

I/O and Expandability

As a 2U system, the DL380 Gen10 offers excellent expansion capabilities:

• Up to 8 PCIe 3.0 slots for network adapters, storage controllers, or GPUs
• Support for HPE FlexibleLOM and OCP mezzanine adapters for 1GbE, 10GbE, 25GbE, or 100GbE networking
• GPU support for up to 6 single-width or 3 double-width GPUs
• Optional rear drive bays for additional storage expansion
  

This expandability makes the DL380 Gen10 highly adaptable to a variety of workload demands, from AI/ML acceleration to high-throughput networking.

Virtualization and Use Cases

The HPE ProLiant DL380 Gen10 is optimized for:

• Virtualization with VMware vSphere, Microsoft Hyper-V, and KVM
  
• Cloud and hybrid deployments running software-defined storage or infrastructure
• Database workloads including SQL, Oracle, and in-memory platforms
• AI/ML training, VDI deployments, and enterprise applications
• Data analytics and content delivery
  

Its combination of processing power, memory capacity, and flexible storage makes it a workhorse for data centers needing reliable and adaptable infrastructure.

Management and Automation

The DL380 Gen10 includes HPE iLO 5 for enterprise-grade remote server management:

• Silicon Root of Trust for firmware-level security
• Full remote console with virtual media support
• Integration with HPE OneView for infrastructure automation
• HPE InfoSight for AI-driven analytics and proactive issue resolution
• Simplified deployment with Intelligent Provisioning and scripting tools
  

These features allow IT teams to manage large server fleets efficiently and securely from anywhere.

Energy Efficiency

The DL380 Gen10 is engineered for optimized power usage:

• 80 PLUS Platinum and Titanium-certified power supplies
• HPE Power Discovery Services for intelligent power distribution
• Dynamic power capping and workload balancing
• ASHRAE A3/A4 compliance for energy-efficient operation in extended temperature ranges
  

This makes it an eco-conscious choice without compromising performance.

Reliability and Availability

Designed for mission-critical uptime, the DL380 Gen10 offers:

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  , TPM 2.0, and runtime firmware validation
  
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These reliability features ensure that workloads keep running even in the event of hardware issues.

Key Features at a Glance:

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  Dual Intel Xeon Scalable CPUs (up to 56 cores total)
  
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  Up to 3.0TB DDR4 SmartMemory with ECC and Intel Optane support
  
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  Flexible mix of SAS, SATA, and NVMe drives; up to 30 SFF or 20 LFF bays
  
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  Up to 8 PCIe slots, GPU support, OCP/FlexibleLOM networking
  
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  Certified for VMware, Hyper-V, and KVM
  
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  iLO 5, HPE OneView, Intelligent Provisioning, HPE InfoSight
  
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  Platinum/Titanium PSUs, dynamic power management
  
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  Hot-swap redundancy, Silicon Root of Trust, advanced security
  

Business Value

The HPE ProLiant DL380 Gen10 is a flagship enterprise server that delivers outstanding flexibility, scalability, and security in a balanced 2U design. Its ability to adapt to different workloads, from virtualization and cloud hosting to big data and AI, makes it an invaluable asset for modern data centers. With enterprise-grade reliability, simplified management, and investment protection through upgradable components, the DL380 Gen10 provides both immediate performance benefits and long-term business value.